powder for oral administration
Description
Powder, white-coloured.
Composition
100 g of the drug contains:
active ingredient: fenbendazole – 22.2 g;
Excipient: starch.
powder for oral administration
Description
Powder, white-coloured.
Composition
100 g of the drug contains:
active ingredient: fenbendazole – 22.2 g;
Excipient: starch.
Pharmacological properties
АТС vet QP52 — Antihelmintics. QP52AC13 — Fenbendazole.
The active ingredient – fenbebdazole (group of benzimidazoles) inhibits polymerization of proteins of tubulins in microtubules, decreases activity of energetic enzymes. The drug causes disturbance in metabolism in helminths, resulting in reduction of glucose uptake, mitochondrial reactions and cell mitosis disorder. These processes result in complete devastation and death of parasites.
Fenbendazole is a broad-spectrum antihelmintic of helminthagogue action. Fenbendazole is is highly effective against most types of gastrointestinal and lung nematodes, certain cestodes, trematodes, acantocephala (at every development stage). It has an ovocidal action.
Orally administered fenbendazole is primarily excreted unchanged in feces as metabolites. About 1% is excreted in urine. Resorbed fenbendazole accumulates primarily in liver and fat tissues.
Half-life makes 26 hours in sheep, — 25 hours in cattle and 10 hours in swine. and 10 hours in swine.
Administration
Prevention and treatment of the following parasite invasions in cattle, sheep, goats, horses, swine, poultry (hens, turkeys, geese, ducks), rabbits, fur animals (Arctic foxes, foxes), carnivores (dogs, cats):
cattle, sheep, goats: Haemonchus spp., Nematodirus spp., Bunostomum spp., Oesophagostomum spp., Trichostrongylus spp., Ostertagia spp., Cooperia spp., Сhabertia ovina, Trichuris spp., Strongyloides spp., Dictyocaulus spp., Protostrongylus spp., Moniezia spp., Avitellina centripunctata, Dicrocoelium lanceatum, Paramphistomum spp., Liorchis scotia, Gastrothylax crumenifer;
horses: Parascaris equorum, Oxyuris equi, Strongylus spp., Triodonthophorus spp., Сiathostomum spp., Cylicocyclus spp., Strongyloides spp., Anoplocephala magna, A. perfoliata, Paranoplocephala mamillana;
swine: Ascaris suum, Trichuris suis, Oesophagostomum dentatum, Ollulanus spp., Strongyloides ransomi, Metastrongylus spp.;
poultry: Ascaridia spp., Heterakis gallinarum, Syngamus trachea, Capillaria spp., Ganguleterakis dispar, Amidostomum anseris, Tetrameres fissispina, Hymenolepis spp., Drepanidotaenia spp., Polymorphus spp., Filicollis anatis;
rabbits: Passalurus ambiquus, Trichostrongulus spp.;
fur animals: Toxocara spp., Ascaris spp., Toxascaris spp., Ancylostoma caninum, Uncinaria stenocephala, Capillaria spp., Strongyloides spp., Molineus patens;
dogs: Toxocara canis, Toxascaris leonina, Ancylostoma caninum, Uncinaria stenocephala, Trichuris vulpis, Taenia spp., Oslerus osleri, Protozoa - Giardia (Lamblia) spp.;
cats: Toxocara mystax, Ancylostoma tubaeforme, Taenia spp., Aelurostrongylus abstrusus.
Dosage
Administer the drug orally as a single dose, having preliminarily mixed it with feed, better – during the morning feeding in the following doses:
Animal species, disease | Single dose (g/kg body weight) |
Frequency and duration of treatment | ||
Fenotal powder, 22.2% | Fenbendazol. | |||
Cattle . . | Nematodosis, cestodosis | 0.07
| 0.015
| Once a day for 2-3 days |
Dicroceliosis, paramphistomatidosis | 0.07
| 0.015
| Once a day for 6 days | |
Sheep, goats | Dictiocaulosis, protostrongyloidosis, trichuriasis | 0.07 | 0.015 | Once a day for 2-3 days |
Gastrointestinal strongyloidosis, strongyloidosis, cestodosis | 0.045 | 0.01 | Once a day for 2 days | |
Dicroceliosis, paramphistomatidosis | 0.07
| 0.015
| Once a day for 6 days | |
Horses | Parascarosi, oxiurosis, anoplocephalidosis | 0.07 | 0.015 | Once a day for 2 days |
Gastrointestinal strongylatosis | 0.045 | 0.01 | Once a day for 5-6 days | |
1-2 month old colts: diarrhea caused by Strongyloides westeri | 0.036
| 0.008 | Once a day for 2 days | |
Swine
| ascorydosis, metastrongylosis, trichurrosis, esophagostomosis | 0.07
| 0.015 | Once a day for 5-6 days |
olulanosis, strongyloidosis | 0.045 | 0.01 | Once a day for 2-3 days | |
Hens, turkeys: mixed nematode invasion | 0.045
| 0.01 | Once a day for 5-6 days | |
Geese, ducks | Nematodosis, cestodosis (mixed invasion) | 0.18 | 0.04 | Once |
acanthocephaliasis | 0.09 | 0.02 | Once a day for 5-6 days | |
Rabbits: mixed nematode invasion
| 0.045
| 0.01 | Once a day for 3 days | |
Fur animals (Arctic foxes, foxes): mixed nematode invasion | 0.045
| 0.01 | Once a day for 5 days | |
Dogs, cats: Nematodosis, cestodosis | 0.225 | 0.05 | Once a day for 3 days | |
Puppies and kittens, min. 3 weeks old: protosoosis - giardiasis (lambliasis), as well as nematodosis, cestodosis, | 0.14
| 0.03 | Three days in every 12 hours | |
Contraindications
Do not administer to emaciated animals and animals with infectious diseases!
Precautions
Do not administer the drug in combination with anti-fascioliasis drugs as well as in 7 days following treatment with bromsalans.
Slaughter of cattle, sheep, goats, horses, swine for meat is possible in 10 days, following the last administration, poultry — in 3 days, Milk can be consumed in 2 days following the last administration. Meat obtained before the mentioned term shall be utilized, fed to carnivores or processed into meat and bone flour.
Packaging
Polymer jars, polyethylene or laminated bags of 100, 500 and 1 000 g.
Storage
Store in a dark place out of the reach of children at 5-30 °С.
Shelf life
2 years.
For use in veterinary medicine!